Bio Saga Headlines

Bio Saga

Wednesday, February 29, 2012

Workshop/ Seminar / Training In Biotechnology in India 2012


Monday, February 27, 2012

Opportunities at Genbios

Genbios welcomes talented and committed people who wish to work alongside the best minds. If you hold a Ph.D or a Masters in Bioinformatics, Biotechnology, Microbiology, Software Engineering and Business Management, we invite you to be a part of the Genbios team. Please email your resume only to info@genbios.in

Current vacancies:

Data curator and Analyst

Qualification: Graduate/ Post-graduate/ Diploma in Bioinformatics
The job profile includes
  • Literature survey
  • Collection and curation biological data
  • Bioinformatics analysis of data
  • Database creation and management
Skill set:
  • Bioinformatics: A complete knowledge of the most commonly used bioinformatics databases and tools
  • Information Science: Good knowledge in application of various programming languages such as Perl, Perl-CGI, Java, MySQL, PHP and related technologies for Bioinformatics. Experience in Linux environment is an advantage
  • Life sciences: A very sound basic knowledge of biology is necessary.
  • Good communication skills, fluent in reading and writing English, ability to work in teams, independent and innovative thinking, enthusiasm at work and an open mindedness for learning.

Senior Software engineer

Qualifications required: B.E/ B-Tech/ M.E/M.Tech/ MCA/ Diploma in Computer Science/ Bioinformatics
The job profile includes:
  • Programming in PERL and Java
  • Application of various Bioinformatics tools
  • Usage RDBMS for database creation
  • Managing all the software needs of the company
Skill set:
  • Information Science: Perl, Perl-CGI, BioPerl, Java, MySQL, PHP and related technologies, Experience in Linux environment
  • Life sciences: Basic knowledge
  • Good Communication skills, ability to work in teams, independent, innovative thinking with an open mind for learning and enthusiasm to work

Business Development Executive

Qualifications required: MBA/ BBM with 2 years of experience in business development in life sciences industry
The job profile includes:
  • Sales of existing services and tools
  • Addition of new clientele and projects
  • Business expansion of the company
Skill set:
  • A good ability to expand business
  • Information Science: Basic knowledge
  • Life sciences: A good knowledge
  • Good Communication skills, ability to work in teams, independent, innovative thinking with an open mind for learning and enthusiasm to work

Friday, February 24, 2012

Free online courses from Stanford's Coursera, MIT's MITx, and Udacity

Class Central

Summary of free online courses from Stanford's Coursera, MIT's MITx, andUdacity
UPCOMING 15 COURSERA COURSE(S) 1 MITX

Ten Years of Pathway Analysis: Current Approaches and Outstanding Challenges

Pathway analysis has become the first choice for gaining insight into the underlying biology of differentially expressed genes and proteins, as it reduces complexity and has increased explanatory power. We discuss the evolution of knowledge base–driven pathway analysis over its first decade, distinctly divided into three generations. We also discuss the limitations that are specific to each generation, and how they are addressed by successive generations of methods. We identify a number of annotation challenges that must be addressed to enable development of the next generation of pathway analysis methods. Furthermore, we identify a number of methodological challenges that the next generation of methods must tackle to take advantage of the technological advances in genomics and proteomics in order to improve specificity, sensitivity, and relevance of pathway analysis.

Wednesday, February 22, 2012

TS-AMIR: A Topology String Alignment Method for Intensive Rapid Protein Structure Comparison

In structural biology, similarity analysis of protein structure is a crucial step in studying the relationship between proteins. Despite the considerable number of techniques that have been explored within the past two decades, the development of new alternative methods is still an active research area due to the need for high performance tools. Results: In this paper, we present TS-AMIR, a Topology String Alignment Method for Intensive Rapid comparison of protein structures. The proposed method works in two stages: In the first stage, the method generates a topology string based on the geometric details of secondary structure elements, and then, utilizes an n-gram modelling technique over entropy concept to capture similarities in these strings. This initial correspondence map between secondary structure elements is submitted to the second stage in order to obtain the alignment at the residue level. Applying the Kabsch method, a heuristic step-by-step algorithm is adopted in the second stage to align the residues, resulting in an optimal rotation matrix and minimized RMSD. The performance of the method was assessed in different information retrieval tests and the results were compared with those of CE and TM-align, representing two geometrical tools, and YAKUSA, 3D-BLAST and SARST as three representatives of linear encoding schemes. It is shown that the method obtains a high running speed similar to that of the linear encoding schemes. In addition, the method runs about 800 and 7200 times faster than TM-align and CE respectively, while maintaining a competitive accuracy with TM-align and CE. Conclusions: The experimental results demonstrate that linear encoding techniques are capable of reaching the same high degree of accuracy as that achieved by geometrical methods, while generally running hundreds of times faster than conventional programs.

University of Hyderabad: Faculty positions

courtesy bioclues

The University of Hyderabad has extended the date for submission of 
application forms upto 13th  March, 2012 for all the teaching positions 
notified at the level of Assistant Professor, Associate Professor and Professor 
in its various Schools, Departments and Centres in the above 
advertisement. For details including eligibility criteria, application fee, detail 
of posts etc, please visit the University Website  www.uohyd.ernet.in or 
www.uohyd.edu.in . All other terms and conditions shall remain the same.

Thursday, February 16, 2012

C-DAC makes new supercomputer, Biochrome, to aid biology research

The Pune-based Centre for Development of Advanced Computing (C-DAC), maker of series of high-end PARAM supercomputer, has developed a new powerful supercomputer called Biochrome to aid computational biology research with an investment of Rs 1 crore, a top official said.

“The Biochrome machine is an advanced blade server based high performance computing (HPC) facility developed by our scientists to aid biology researchers in the country and abroad,” Professor Rajat Moona, director general of C-DAC, said. The machine has a peak computing capacity of 5 TeraFlop or the capacity to perform 5 trillion operations per second.

“About 10 scientists from C-DAC spent over six months to design and produce Biochrome machine with a total investment of Rs 1 crore funded by the Department of Information Technology, government of India,” Rajendra Joshi, associate director and head of the department of Bioinformatics, C-DAC, who headed the research team, said. He said Biochrome is the latest product from Bioinformatics Resources and Applications Facility (BRAF) at C-DAC, to be used for high-end computation for bioinformatics. “Biochrome cluster can be accessed by researchers from industry and academia for research work,” Joshi said.

He said BRAF is an effort towards providing high-end supercomputing facility to the researchers working in the areas of life sciences. He said next generation sequencing technology had brought in a new dimension to understand the molecular basis for the occurrence of diseases.

“The next generation sequencing technology enables sequencing of hundreds of genomes at an extremely rapid rate and at a significantly lower cost,” Joshi said. To be able to generate knowledge from the oceans of genomic data, enabling technologies like high performance computing, grid computing and cloud computing were the latest weapons in the hands of modern biologist, he said.

Joshi said BRAF was also setting up an advanced Cyberinfrastructure for life sciences in collaboration with National Cancer Institute of National Institute of Health, USA, Tata Memorial Centre, Mumbai, Roslin Institute, UK, University of Edinburgh, UK, University of Surrey, UK, Oregon Health and Science University, USA, National Centre for Cell Science, Pune, IIT, Chennai and National Chemical Laboratory, Pune.

Wednesday, February 15, 2012

2012 1st Journal Conference on Bioscience, Biochemistry and Bioinformatics

    2012 1st Journal Conference on Bioscience, Biochemistry and Bioinformatics (JCBBB 2012 1st) aims to provide a forum for researchers, practitioners, and professionals from the industry, academia and government to discourse on research and development, professional practice in bio science, biochemistry and bioinformatics. Date of the conference-10-12 March,2012 Venue-Chennai,TN For further details,please refer to the link http://www.ijbbb.org/jcbbb/1st/index.htm

Monday, February 13, 2012

3rd INTERNATIONAL CONFERENCE on BIOINFORMATICS AND SYSTEMS BIOLOGY

3rd INTERNATIONAL CONFERENCE
on
BIOINFORMATICS AND SYSTEMS BIOLOGY

(INCOBS-2012)
16th -18th February, 2012
ANNOUNCEMENT
&
CALL FOR PAPER
Organised by
DEPARTMENT OF ZOOLOGY(DDE)
Annamalai University
Annmalainagar-608002
Tamilnadu, India
Do you wish to know more?

Thursday, February 9, 2012

Positions for Freshers

Cactus Communications is a pioneering language services company serving more than 25,000 clients across 73 countries. In line with its mission—growth through effective communication, Cactus offers specialist academic editing, medical communications, publication support, transcription, and training services to individuals and corporations across sectors such as academia, publishing, and pharmaceuticals. 
A global healthcare leader, Novartis has one of the most exciting product pipelines in the industry today. A pipeline of innovative medicines brought to life by diverse, talented and performance driven people. All of which makes us one of the most rewarding employers in our field. Designation : Specialist – CSD Job Description
Jubilant Biosys Ltd, is a part of the Jubilant LifeSciences family of companies with R&D centers in India and the USA and business offices in Asia and North America. Jubilant Biosys has global reach and provides comprehensive drug discovery services – from target discovery to clinical development in partnership with leading healthcare companies worldwide.
GE Healthcare provides transformational medical technologies that are shaping a new age of patient care. GE Healthcare’s expertise in medical imaging and information technologies, medical diagnostics, patient monitoring and life support systems, disease research, drug discovery, and biopharmaceutical manufacturing technologies is helping physicians detect disease earlier and to tailor personalized treatments for patients. GE Healthcare 


Monday, February 6, 2012

Bio Saga - Live Projects & Internship

3 Industry facilities open for Internship & Live Projects,
  • 2 well equipped labs providing Drug Discovery Internships;
  • 1 providing hands on live training and live project on NGS & microarray data analysis

  • who can benefit?

1) Industry people who wish to upgrade and equip themselves
2) Researchers in research facilities, govt. & academics
3) Students & Freshers (Job assistance provided)
for more info write tojkamesh@gamil.com

FREE! Online MATLAB workshop

    MATLAB Workshop at Univ. of Oklahoma and via videoconferencing Morning: Data Analysis with MATLAB (no previous MATLAB experience needed) Afternoon: Parallel Computing with MATLAB WHEN: Tue Feb 28 2012, 10:00-11:30am and 1:00-3:30pm Central Time WHERE: University of Oklahoma, Stephenson Research & Technology Center COST: *FREE* SESSION I: Data Analysis with MATLAB (No previous MATLAB experience needed) 9:45-10:00am Central Time: Registration and check-in 10:00-11:30am Central Time: Data Analysis with MATALB Engineers, scientists, and data analysts worldwide use MATLAB to accelerate research and to reduce analysis and development time. Attend this seminar to find out how you and your colleagues can use MATLAB and its add-on products to analyze your data more effectively and to overcome some of the limitations you face when using spreadsheets for data analysis. We will provide an overview of MATLAB through live demonstrations showing how to: * Access data from many sources (files, other software, hardware, etc.) * Use interactive tools for iterative exploration, design, and problem solving * Automate and capture your work in easy-to-write scripts and programs * Share your results with others by automatically creating reports. No previous MATLAB experience is needed for Session I. SESSION II: Parallel Computing with MATLAB Prerequisite: Session I, or equivalent MATLAB experience 12:45-1:00pm Central Time: Registration and check-in 1:00-3:30pm Central Time: Parallel Computing with MATLAB In this session, you will learn how to solve computationally and data-intensive problems using multicore processors, GPUs and computer clusters. We will introduce you to high-level programming constructs that allow you to parallelize MATLAB applications without CUDA or MPI programming and to run them on multiple processors. We will also show you how to overcome the memory limits of your desktop computer and to solve problems that require manipulating very large matrices by distributing your data. Highlights will include: * Toolboxes with built-in support for parallel computing * Creating parallel applications to speed up independent tasks * Programming with distributed arrays to work with large data sets * Scaling up to computer clusters, grid environments, or clouds * Tips on developing parallel algorithms Special add-on session: A representative from OU will offer information for OU MATLAB users who are interested in running MATLAB jobs on OU's supercomputing resources. PRESENTER BIOGRAPHY Gerardo Hernandez Correa holds a BS in Physics and an MS in Applied Mathematics from the University of Puerto Rico at Mayag├╝ez, and an MS in Mechanical Engineering from Worcester Polytechnic Insititute (WPI). He is currently completing the requirements for a PhD in Mathematical Sciences, also at WPI. At UPRM, his area of research was the theory of distributions and inverse problems, in particular the identification of linear systems. In his MS thesis, "Identification of Linear Systems," Gerardo designed and implemented in MATLAB an iterative, non-destructive method for retrieving the convolution kernel of linear systems. At WPI, in his dissertation, "An Adaptive, Multiresolution Agent-based Model of Glioblastoma Multiforme", Gerardo designed and implemented in MATLAB a multi-resolution agent-based model of the evolution of brain tumors, in particular Glioblastoma multiforme. Gerardo's areas of interest include numerical methods -- in particular Ordinary and Partial Differential Equation solvers -- as well as mathematical modeling, dynamical systems and high performance computing, among others.

Sunday, February 5, 2012

Application Support Specialist Job at Monsanto


Monsanto is a Fortune 500 Company, headquartered in St. Louis, Missouri. It has more than 20,000 employees at 320 locations worldwide in four primary regions – Europe/Africa, Asia Pacific, Latin America and North America. It has $11.7 billion in annual sales. In India, it started his operation in 1949 and is headquartered in Mumbai.
Post : Application Support Specialist – Contract
No of Post : Two
Experience : 3 to 7 years
Location : Bangalore
Job Description : The successful candidate will become a member of Technology Pipeline Solutions (TPS) Team, part of Monsanto IT systems, supporting enterprise-level biotech and breeding related software applications. This is a very domain intensive role and will require deep understanding of various concepts in breeding, Biotechnology and data base applications.
Job responsibilities :
1. Quick grasping of enterprise applications and their usage
2. Train the scientific community and ensure effective utilization of applications
3. Day to day interaction with scientists and breeders to provide quality & timely support
4. Proactive in identifying the customer needs, arriving at probable solutions, working closely with IT teams for better solutions
5. The individual will need to interact closely across global teams
Educational Qualification : B.Sc – Agriculture, Bio-Chemistry, Biology, Botany AND M.Sc – Agriculture, Bio-Chemistry, Biology, Botany
Desirable :
a. More then 3 years of Breeding/Plant/Biotech Research experience
b. Work experience with scientific data base/ Bioinformatics applications is desirable.
c. Strong oral and written communication skills, collaboration and networking skills across scientific and international teams, self motivated, strong team player
Contact Details :Executive Name : Rahul Anand
Email Address : rahul.anand@monsanto.com
Deadline : 02.03.12

Friday, February 3, 2012

Sunshine Wellness Studio

Sunshine Wellness Studio:

"We are each gifted in a unique and important way. It is our privilege and our adventure to discover our own special light"
~Mary Dunbar

Sunshine is a professionally managed Wellness Studio that uses various modalities of clinical hypnotherapy, energy work and crystals for the purpose of healing. Founded and managed by Sri Ram, the success of the concept and this organization can be attributed besides Divine sanction, to what could be termed as the "inner calling" to understand, connect to people and to help heal. Over the years, clients have healed out of physical ailments, found answers in their quest, manifested goals, career changes, riches and so on.

Thursday, February 2, 2012

Protein drugs to facilitate easier treatment of cancer

Scientists have discovered a new physical form of proteins that could drastically improve treatments for cancer and other diseases, as well as overcome some of the largest challenges in therapeutics.
The protein formulation strategy, developed by researchers at The University of Texas at Austin, is unprecedented and offers a new and universal approach to drug delivery one that could revolutionize treatment of cancer, arthritis and infectious disease.
“We believe this discovery of a new highly concentrated form of proteins – clusters of individual protein molecules – is a disruptive innovation that could transform how we fight diseases,” Keith P. Johnston, a chemical engineering professor and member of the National Academy Engineering, said.
“It required integration of challenging contributions in fundamental science and engineering from three of our chemical engineering research groups,” he said.
Johnston, Chemical Engineering Professor Thomas M. Truskett and Assistant Professor Jennifer Maynard have led the research.
“The real challenge in developing therapeutics is how do you deliver them to patients,” Maynard said.
Typically, protein biopharmaceuticals are administered intravenously at dilute concentrations in a hospital or clinic. Scientists and engineers have long tried to produce safe drugs at higher concentrations, so that a patient could self-inject the drugs at home, similar to an insulin shot.
However, doing so has been stymied by the fact that proteins, in high-concentration formulations, form aggregates that could be dangerous to patients and gels that cannot be injected.
The Cockrell School research team has introduced a new physical form of proteins, whereby proteins are packed into highly concentrated, nanometer-sized clusters that can pass through a needle into a patient to treat disease.
The novel composition avoids the pitfalls of previous attempts because drug proteins are clustered so densely that they don’t unfold or form dangerous aggregates.
“This general physical concept for forming highly concentrated, yet stable, protein dispersions is a major new direction in protein science,” Johnston said.
A key advance came in 2004, when Truskett predicted that protein-based drugs in solution would be stable if they could somehow be formulated at ultra-high concentrations. At that time, Johnston had nanoparticles of concentrated stable protein but didn’t know how to disperse them in an injectable form.
In 2009, the team formed protein nanoclusters in water simply by properly adjusting the pH (to lower protein charge) and adding sugar to crowd protein molecules together. Upon dilution or subcutaneous injection into a mouse the proteins separate back to individual stable molecules with biological activity.
Once injected, the protein in the bloodstream attacks targeted cells and tumors similarly as for protein delivered via IV therapy. To provide a roadmap for improving the design of nanoclusters, chemical engineering graduate students, Andrea Miller and Ameya Borwankar worked with Truskett and Johnston to develop a new thermodynamic theory.
Another breakthrough for the team came in 2009 when a chemical engineering senior, Brian Wilson, created a transparent dispersion of extremely concentrated protein, which was later found to be formed of nanoclusters.
The study has been published online in the ACS Nano journal.

Life Science and Informatics

What is this?
is this a new industry?
or a old wine in a new bottle?

Well Life Sciences and Informatics can be anything form computational biology, all omes and omics, core bioinformatics to curation and literature mining, database creation, in the area of biology, chemistry , bio-chem space.

There are number of companies in India and bangalore is the forefront as a major bio-cluster with 20 to 30 companies in this sphere.

now how good are these companies doing?
how good are they in terms of the international markets and how profitable is their business?
what do they do?
their clients?

These are some interesting things that could be discussed in this blog page...

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