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Wednesday, March 28, 2012

National Conference/Workshop "Search for Antimalarials:Mechanism Based Approach"

National Conference-cum-Workshop on "Search for Antimalarials:Mechanism Based Approach"
27th - 29th April, 2012



The workshop will cover the following topics

  • Malaria Genomics/Proteomics
  • Malaria Vaccine Development
  • Current scenario of Malaria Drug Development
  • Drug Target Validation and Proritization
  • Structural Bioinformatcs/chemoinformatics
  • Malaria Drug Target Database Development
  • Target  Based Drug Designing
  • Target-drug interaction mapping
  • 3DQSAR and Pharmacophore Design
  • Antimalarial Database Development


All correspondence for the National Conference cum workshop should be addressed to :
Dr. Naidu Subbarao
School of Computational and Integrative Sciences
Hall No. 6, Lecture Hall Complex
Jawaharlal Nehru University
New JNU Campus, New Delhi 110 067
Email:nsrao@mail.jnu.ac.in / nsrao.jnu@gmail.com


Do you wish to know more?


Tuesday, March 27, 2012

Drug Safety Associate position @ Avesthagen


Avesthagen- a life science company in Bangalore has an opening for Drug Safety Associate. 


Details: 
   - Experience : 0 to 3 yrs
   - Job description : Database programmer will develop complex edit
   checks based on study requirements & Programming of complex edit checks,
   including cross-form edit checks, in order to identify discrepancies in the
   data recorded on CRFs and on eCRFs 


   - Salary : Best in the Industry
   - Education : M.Sc - Biology, M.Tech - Bio-Chemistry/Bio-Technology, Biomedical Science 



Send your CV to: crtraining@avesthagen.com, yasmin@avesthagen.com 


Deadline : 22.04.12 

Monday, March 26, 2012

Disulphide Redox Metabolic Database of genus Listeria

Listeria TDRM Database http://www.lmtdrm.com/. Please keep your comments and suggestions flowing in kamesh@pronetinformatix.com

The genus Listeria consists of a group of gram-positive bacteria of low G+C content closely related to Bacillus, Clostridium, Enterococcus, Streptococcus, and StaphylococcusListeria spp. are facultative anaerobic rods of 0.4 by 1 to 1.5 ┬Ám that do not form spores, have no capsule and are motile at 10 to 25°C. Listeria spp. is isolated from a diversity of environmental sources, including soil, water, effluents, a large variety of foods, and the feces of humans and animals. The genus Listeria currently includes eight species: L. monocytogenesL. ivanoviiL. seeligeri,L.rocourtiaceL. innocuaL. welshimeriL. marthii and L. grayi. Two of these species L. monocytogenes and L. ivanovii are potentially pathogenic. The infectious disease caused by these bacteria is known as listeriosis. L. monocytogenes causes serious localized and generalized infections in humans and a variety of other vertebrates, including domesticated and wild birds and mammals. Human cases of L. ivanovii infection are rare the vast majority of reported isolations of this species being from abortions, stillbirths and neonatal septicemias in sheep and cattle. A third species L. seeligeri is considered nonpathogenic. Recently L. grayi DSM 20601 has been reportedinfectious to immmunocompromised patients.

Synthesis of glutathione a low-molecular-weight peptide thiol was thought to occur solely through the consecutive action of two physically separate enzymes, gamma-glutamylcysteine ligase and glutathione synthetase. But it has been identified that L. monocytogenes contains a novel multidomain protein (termed GshF) that carries out complete synthesis of glutathione. It is a 776 amino acid fusion protein and fusion occurs in 338 to 580 amino acids.It is coded by the gene Lmo 2770 in L. monocytogenes.

Thiol:disulfide redox metabolism (TDRM) is a central metabolic network in all living cells. In L.monocytogenes, we have identified 26 genes that belong thiol disulphide network. L. monocytogenes-Thiol: Disulphide Redox Metabolism database provides information on Thiol disulphide redox gene and gene products. This database also provides information about the Gene and Domain Annotation, Clustering, Structure Details. TDRM analysis gives detailed analysis of the similar cluster of these TDRM genes across bacterial species consisting 82 bacterial strains. With the help genome browser, user can view the TDRM genes on the genomic scale and analyze the same.

OBJECTIVES
  1. Understanding TDRM genes on the genomic scale with reference to other GshF containing bacteria
  2. Finding the genes which have probable role in thiolomics in L. monocytogenes EGD-e
  3. Genetic context of the relevant genes in Listeria with other bacteria and their annotations



Monday, March 19, 2012

Microbial Genomes Curator @ Computercraft Corporation--Maryland (US)

Microbial Genomes Curator @ Computercraft Corporation--Maryland (US). Submitted by Computercraft Corporation; posted on Saturday, March 17, 2012

RESPONSIBILITIES:
Computercraft seeks a microbiologist to work with a team of software developers and biologists on microbial genome analysis including pan-genome, protein clusters, phylogenetic tree and more. This is a technically challenging position requiring experience in genome sequencing and annotation. A background in comparative genome analysis such as alignments and tree building is a plus.

Our scientists work with genomic experts at the NIH's National Center for Biotechnology Information (NCBI) to create and enhance a suite of databases and tools available to researchers worldwide. Teamwork interaction and excellent organizational skills are essential for this detail-oriented position, as is scientific problem-solving with a results-oriented focus.

REQUIREMENTS:
* PhD in molecular biology, microbiology, or related field
* Experience in genome sequencing and annotation
* Familiarity with BLAST, genome browser, and genome assembly data
* Excellent verbal and written communication skills as well as organizational skills
* Strong interest in contributing to the development of public database resources

PREFERENCES:
Other Desirable Skills:
* Programming experience with LINUX/UNIX
* Scripting experience in PERL or related scripting languages

COMPENSATION:
Computercraft offers a competitive salary and an excellent benefits package including PPO health insurance with 100% company paid premiums, 401K program with matching, paid time off and holiday pay, life insurance, flexible spending and disability coverage. We offer an excellent work life balance with a standard 40 hour work week and the chance to work alongside accomplished scientists at NIH/NCBI.

HOW TO APPLY:
To apply for this position or learn about other Computercraft job opportunities, please visit the Careers section of our website: http://www.computercraft-usa.com/

POLICY:
Computercraft is an equal opportunity employer.

Post Doctoral Fellow in Wellcome Trust DBT India Alliance project at NII, New Delhi

Applications are invited for the post of Post Doctoral Fellow for the following time-bound sponsored project as per the details given below:
Post : Post Doctoral Fellow
  • Consolidated fellowship : As per terms governed by the Wellcome trust DBT India Alliance and National Institute of Immunology (a Minimum of Rs. 40,000/- per month). 
  • Project title : Exploring the role of a developmental regulator in inflammatory immune response under Wellcome Trust DBT India Alliance
Essential Qualification : a. Must hold a Ph.D Degree (not awarded before 2009), or must already have submitted their thesis towards obtaining a Ph.D degree from a reputed Institute.
b. Must have more than Five years of research Experience.
c.  Must have proven research expertise/skills in basic biochemistry, cell biology and Molecular Biology, Research Expertise in in vivo animal work is also preferred.
d. Must have one publication as first author, in international journal, preferably with impact factor above 2.5.
e. Must have basic theoretical knowledge in the area such as cell signalling, inflammation, Immunology.
  • Job description/Experience : The Candidate is ready to explore alteration in the host cell signalling and transcription network in response to pathogenic perturbations. The Candidate should have sound technical skills in cell culture and biochemistry and should have working theoretical knowledge in cell signalling. The candidate must have a Ph.D Degree (or must have submitted his/her thesis towards obtaining a Ph.D degree) and more than 5 years of experience in research laboratories. 
Duration : 30.11.2015
PI : Dr. Soumen Basak | sobasak@nii.ac.in  
How to Apply :Interested candidates may apply directly, STRICTLY IN THE PRESCRIBED FORMAT GIVEN ON WEBSITE through e-mail, to the Investigator of the project, clearly indicating the name of the project along with their complete C.V., e-mail id, fax numbers, telephone numbers. Short listed candidates will be required to submit attested copies of all their certificates and a Demand Draft of  Rs 100/- drawn on Canara Bank or Indian Bank payable at Delhi / New Delhi in favour of the Director, NII (SC / ST and PH candidates are exempted  subject to submission of documentary proof), at the time of interview.
Deadline : 28.03.12

Friday, March 16, 2012

Freshers in BioChemistry/ Biotechnology/ Bioinformatics as Research Associate at Bigene Technologies, TN

Bigene Technologies in Trichy requires fresher candidate for Research Associate in Bioinformatics
Post : Research Associate
No of Opening : One
Experience : 0 to 1 yrs
Job Desciption : The bioinformatics team is seeking an energetic, creative and detail oriented
research associate. The cart informatics and statistical tools to analyze the data. Ability to quickly grasp mathematical concepts an essential. The candidate will spend significant time interacting with life scientists in multiple disease areas.
Salary : INR 1,50,000 – 3,00,000 P.A
Education : M.Sc – Bio-Chemistry, Biotechnology, Bioinformatics
Desirable :1. Candidate should have basic knowledge in computer programming
2. Good written and presentation skills required
3. Excellent communication and interpersonal skills combined with superior and proven track record of technical. Must be able to work in team oriented environment and demonstrate attension to detail and record keeping.
Location : Trichy
Contact Details :Executive Name : Jaganathan M. P.
Contact Company : Bigene Technologies
Email Address : careers@bigenetech.com
Deadline : 27.03.12

Bioinformatics Bacterial Identification Tool

    BIBI automates DNA sequence analysis for bacterial identification in
    the clinical field. BIBI relies on the use of BLAST and CLUSTAL W
    programs applied to different subsets of sequences extracted from
    GenBank. These sequences are filtered and stored in a new database,
    which is adapted to bacterial identification.

    For further details refer :http://umr5558-sud-str1.univ-lyon1.fr/ lebibi/lebibi.cgi

Thursday, March 15, 2012

Bioprocessing in Biotechnology – Short Term Training Course (STTC) at KCT, Coimbatore


The Department of Biotechnology, Kumaraguru College of Technology (KCT), Coimbatore, is organizing a DBT-sponsored short-term training course (STTC) for teachers involved in teaching life sciences and biotechnology for 14 days from 26 April to 9 May 2012.
The course consists of lectures by Guest Faculty from premier research institutions/universities followed by practical/hands-on training sessions in ratio of 30 : 70.
Candidates holding regular positions in private or govt-aided or govt colleges or university colleges or research institutions are eligible to apply. The application has to be sponsored by the Head of the colleges/institutions/universities. However, 25% of the teachers from govt-aided or govt colleges or university colleges will be paid TA as per institutional rules.
Applications may be sent to The Course Director stating:
1. Name and address for communication (e-mail id, mobile and phone numbers)
2. Educational qualifications and teaching/research experience
3. Present and future research interests (250 words)
Last date for receipt of filled-in application is 25 March 2012. Short-listed applicants will be intimated confirmation on 26 March 2012.
Course Director: Dr P. Ramalingam, Associate Professor, Dept of Biotechnology, KCT, Coimbatore 641 049; Mobile: 098659 23055; e-mail ID: gobiram@rediffmail.com

Open Industry positions for freshers


1. Post : Business Analyst in Pharmaceutical Research
Experience : 0 to 2 yrs
Job Desciption :a. Track the pharmaceutical, biotech and medical devices industry, especially therapeutic areas/modalities of interest to our regular clients
b. Understand project brief given by clients/project leaders, create analysis plan, data requirements, research approach, and prepare reports or executive presentations with key insights and recommendations
c. Report to project leader/consultant and assist in executing or execute the projects completely depending on complexity and scale
Education : M.Sc – Bio-Chemistry, Biotechnology, Life Science
Salary :INR 1,75,000 – 2,50,000 P.A. The CTC is exclusive of Performance Bonus
Desirable :a. High level of comfort with MS Excel, Power Point, ability to perform basic calculations (basic financial, statistical and data manipulation) understand sales and marketing performance metrics, basic data cleaning and organizing, ability to create meaningful charts/ visual representation to simplify complex analyses.
b. Web search, high level of familiarity with life sciences lexicon, regulatory framework for
pharmaceuticals and biotech
c. Attention to detail, accuracy, business relevance in analysis and report writing/executive
presentation skills
Location : Bangalore
Contact Details :Executive Name : Ravi Prakash
Stratycon Business Solutions Pvt Ltd
Address : 14th cross, 2nd block,
Jayanagar Bangalore,Karnataka,India 560011

2. Post : QA Chemist




Gland Pharma Ltd. is a leading Pharmaceutical Company approved by USFDA, involved in Manufacturing and marketing of Small Volume Parenterals, Pre-filled syringes and other Pharmaceutical Products
Experience : 2 to 5 yrs
Job Desciption :a. Should have basic knowledge in sterile injecatble manufacturing.
b. Should be aware of current GMP(CRF/TGA/MCCMHRA) requirements.
c. Good communication and dosumentation skills.
Education : M.Pharma, M.Sc – Bio-Chemistry, Biotechnology, Microbiology
Desirable : Preference will be given to Sterile Injectable working area expereinced candidates.
Location : Hyderabad
Contact Details :Contact Company : Gland Pharma Ltd
Location : Hyderabad
Email Address : hr@glandpharma.com



Tuesday, March 13, 2012

Database Curator@EBI for InterPro database

(EMBL-EBI seeking to recruit an enthusiastic Scientific Database Curator to join the InterPro team at the The European Bioinformatics Institute (EMBL-EBI) located on the Wellcome Trust Genome Campus near Cambridge in the UK.
The post-holder will work as part of a small team maintaining and curating the InterPro database. Their responsibilities will include updating existing InterPro entries, integrating new predictive signatures and adding annotation such as concise, literature-referenced abstracts. Data in InterPro needs to be of a consistently high quality and so potential candidates should have a good attention to detail and a thorough attitude to their work. We believe that understanding our users' needs and providing for them is critically important, and so the curator may be required to attend conferences, workshops or training events in order to meet with users, hear their ideas and expectations, and teach them about InterPro.
The EBI, part of the European Molecular Biology Laboratory (EMBL), provides cutting-edge research, services and training in the field of bioinformatics and is home to world-class resources such as UniProtKB and InterPro. InterPro generates and houses data predicting the functional classification of protein sequences and the presence of protein domains and sites. This information is widely used by genome sequencing projects and is disseminated to a large, global biological research community through web-based databases and software tools.
Requirements: 
The ideal applicant should hold at minimum a BSc. in a Biological Science, preferably with a strong background (e.g. 3 years post-graduate experience) in proteomics, molecular biology, biochemistry, cell biology and/or a related field.
Past work must either include work in a laboratory or in a biological database environment. A good understanding of proteomics and protein evolution would be advantageous, as would a high standard of scientific writing, with experience writing specifically for the web. Familiarity with the use of software tools for nucleotide/amino acid sequence analysis would be an advantage. The role is part of a tightly-knit team, so an ability to communicate ideas and openly discuss potential approaches will be very important. However, applicants should also be able to take their own initiative and work autonomously.
The candidate may be required to describe their work to a wider audience, including end-users of the database, so good presentation skills and an ability to write training materials and teach are a necessity; some of their work may also be published in scientific journals.
No computer programming skills are necessary but a proficiency at using Microsoft Office and a willingness to learn how to use new software tools are a must.
About Our Organization: 
EMBL is an inclusive, equal opportunity employer offering attractive conditions and benefits appropriate to an international research organisation.
Please note that appointments on fixed term contracts can be renewed, depending on circumstances at the time of the review.
Note that special visa requirements apply to employees from non EU countries working at EMBL-EBI in the UK. The period of work does not qualify for the Highly Skilled Migrants Programme.

Sunday, March 11, 2012

Opening for seven Executive posts at Virchow Biotech Pvt Ltd, Hyderabad

Courtesy Bioclues
Virchow Biotech Private Limited (VBPL), an innovative biotechnology company headquartered at Hyderabad, India. VBPL also has offices located in the United States of America ( at Nashville, Tennessee) With an aim of establishing itself in the sunrise industry of biotechnology, Virchow Biotech (P) Ltd commenced its Indian operations in the year 2001. The focus was to develop and manufacture a wide range of unique biologicals and high value bio-generic products at an affordable price. Since then we made impressive strides in terms of product development and have built a strong foundation with a commitment to innovation and process efficiencies. We have rapidly cornered a name for ourselves as a developer of cutting edge therapies in this rapidly evolving biotechnology space.
Post : Executives
  • No of Opening : Seven
  • Experience : 1 to 3 yrs
  • Job Desciption : Candidate must have good knowledge in handling HPLC analytical instrument and water analysis system in Quality Control department.
  • Salary : INR 1,00,000 - 3,00,000 P.A
  • Education : M.Sc - Biology, Bio-Chemistry, Microbiology
  • Location : Hyderabad
Contact Details :Executive Name : Mr.Anil
Contact Company : Virchow Biotech Pvt Ltd
Email Address : hr.virchowbiotech@gmail.com
Deadline : 09.04.12

BIOINFORMATICS & COMPARATIVE GENOME ANALYSES

7 - 19 May, 2012 | Naples | Italy

The course topics will include theoretical and practical aspects in:

  • Large-scale genome comparisons
  • Evolutionary analyses
  • Sequence and genome alignments
  • Orthologs prediction and classification
  • Genome data visualization & Next Generation Sequencing tools & analysis
Theoretical presentations will be followed by practical sessions, so that the same speaker will ensure links between theory and practice.

Reviews on each suggested topic will include their corresponding research perspectives, aiming at helping young scientists to gain insights into ongoing research in this domain.

Practical sessions in a Linux environment will involve Unix shell and Perl scripting. Students are assumed to be familiar with this environment.


Saturday, March 10, 2012

“Research Associate” under the J C Bose Fellowship DST,Govt. of India.

Applications are invited for “Research Associate” under the J C Bose Fellowship Project of DST,Government of India.
Name of the Post : Research Associate
Qualification & Experience : Ph.D.with minimum of 55% marks in M Sc (Theoretical and Computational Chemistry, and allied areas in Biology). Those who have submitted PhD thesis may also apply. Preference will be givento those with published research work of high quality.
Salary : Rs. 22,000/-plus HRA per month.
Age : The upper age limit 35 years on 16.03.2012. A relaxation of 5 years is applicable to candidates belonging to SC/ST/OBC andwomen candidates.
Duration : One Year (extendable for another year, on review of performance)
How to apply: The application should follow the format provided (click here for / format) with this advertisement in the web site (www.iisertvm.ac.in/appointments/projects). Incomplete applications or those that do not meet the minimum criteria will not be considered. Mere fulfillment of qualifications/experience requirements does not entitle a candidate to be called for interview. Only shortlisted candidates will be called for an interview. No TA/DA will be paid to attend the interview. Completed applications should reach the undersigned on or before 16.03.2012 preferably by e-mail (jemmis@iisertvm.ac.in). No communications in this regard will be entertained from candidates.
Dr E D Jemmis
Professor of Chemistry
Indian Institute of Science Education and Research Thiruvananthapuram,
College of Engineering Trivandrum Campus,
Computer Science Building, Engineering College P.O., Trivandrum 695016, Kerala, India.
E-mail: jemmis@iisertvm.ac.in.
Deadline : 16.03.12

Life Science and Informatics

What is this?
is this a new industry?
or a old wine in a new bottle?

Well Life Sciences and Informatics can be anything form computational biology, all omes and omics, core bioinformatics to curation and literature mining, database creation, in the area of biology, chemistry , bio-chem space.

There are number of companies in India and bangalore is the forefront as a major bio-cluster with 20 to 30 companies in this sphere.

now how good are these companies doing?
how good are they in terms of the international markets and how profitable is their business?
what do they do?
their clients?

These are some interesting things that could be discussed in this blog page...

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