Bio Saga Blog - A Chronicle of Life Sciences & Informatics

http://www.nipgr.res.in/careers/vacancies_latest.php Position for Staff Scientists, MA, Tech. Staff (III), Consultant Engineer July 31, 2010 Position for Junior Research Fellow July 12, 2010 Position for Senior Research Fellow, Technical Assistant July 12, 2010 Retired Engineers Courtesy ISCB-RSG-INDIA

Pred_PPI is a web-based system that serves for predicting PPIs from different organisms. This server is freely available to any researcher wishing to use it for non-commercial purposes. Based on auto covariance (AC) and support vector machine (SVM), this tool is capable of predicting PPIs for any target protein pair only using their primary sequences, and assigning an interaction probability to each SVM prediction as well. So the user can use this tool to predict novel PPIs with high confidence. Protein-protein interactions (PPIs) are essential for almost all cellular processes, such as metabolic cycles, DNA transcription and replication, different signaling cascades and so on. However the biochemical methods are all time-consuming and expensive, so current PPI pairs elucidated by experiments are absolutely insufficient compared to the complete PPI networks . Consequently it is increasing important to develop computational tools for effectively identifying PPIs. Check out this one t...

In a paper appearing in the early, online edition of the Proceedings of the National Academy of Sciences yesterday, an international research team reported that they have sequenced the genome of the human body louse , Pediculus humanus humanus . In the process, the researchers also generated sequence that helped them piece together the genome of a bacterial symbiont residing in the louse. Together, the two genomes are providing clues about louse adaptations to obligate parasitism on the human body. In addition, those involved say the work may ultimately provide insights needed to pave the way for more targeted control measures. "Understanding the genome should ultimately open up doors to better understanding how to deal with louse populations," co-senior author Barry Pittendrigh, an entomologist at the University of Illinois at Urbana-Champaign, told GenomeWeb Daily News .

CLC Bio today said that it, along with partners Ion Torrent Systems and Aarhus University Hospital, have received a $2 million grant from the Danish National Advanced Technology Foundation to support a molecular diagnostics collaboration. Under the three-year alliance, the partners aim to develop and integrated hardware and software solution for molecular diagnostics that will utilize high-throughput sequencing. According to CLC Bio, the partners aim to provide faster and more precise DNA-based diagnostics. Earlier this year, Ion Torrent unveiled its Personal Genome Machine, an electronic sequencer last week that reads DNA on a semiconductor chip by measuring the release of hydrogen ions as nucleotides get incorporated by DNA polymerase. The PGM sequencer is a desktop instrument that will cost only $50,000. The Ion PGM sequencer does a single run in about an hour or two. The collaboration will lead to an IT solution that can be used for molecular diagnostics research and for clinical ...

If you’re a scientist or just a science nut, trying to keep up with the latest in the scientific news and commentary via the internet can be a dizzying task. There are literally tens of thousands of blogs ranging from broad overviews of scientific breakthroughs to in-depth coverage of a specific scientific niche. Here is a list of what is considered to be the top 100 cutting-edge science blogs, arranged by category. General These science blogs offer a little bit of everyting. Science Blog : This blog covers anything and everything science. SciGuy : Eric Berger provides readers with current events and insightful commentary. Open Parachute : This blog takes a look at a number of intriguing science topics. Science Musings : Find out about exciting things happeining in science on this blog. LiveScience : This multiple-author blog covers everything from the environment to the animal world. Scientific Frontline Communication Center : Scientific Frontline has everything from weather to space ...

XTractor Lite Try it! on your websites & Blogs

NIH Seeks Comments on Genetic Testing Registry The National Institutes of Health wants to hear what the public thinks about its planned Genetic Testing Registry (GTR), which will be a resource of information for healthcare providers and patients to learn about tests and labs, and for researchers and regulators to watch the genetic testing industry. NIH has opened a 30-day comment period on its GTR project, which will serve as a repository of information about genetic tests submitted by researchers, test developers, and manufacturers. The GTR will include information about how the tests are used, about their validity and utility, and about how they are accessed. The database, which is expected to be running in 2011, will be overseen by the NIH's Office of the Director, and it will be developed by the National Center for Biotechnology Information. "The registry will help consumers and health care providers determine the best options for genetic testing, which is becoming more...

Sandoz has signed a definitive agreement to acquire Oriel Therapeutics, a privately held US pharmaceuticals company, gaining exclusive rights to a portfolio of generic drug candidates and related technologies targeting medicines in the inhalable respiratory drug market. Terms of the deal were not disclosed. The latter focuses on developing respiratory products with known pathways as generic alternatives to patented drugs for asthma and chronic obstructive pulmonary disease (COPD). The acquisition provides the former with three development projects targeting leading medicines in this field. Regulatory approvals of these medicines, if achieved, would enable the former to increase access to affordable, quality therapeutic alternatives for these increasingly prevalent diseases. Details of the latter's development programs, including anticipated timing of future regulatory submissions, are not disclosed for competitive reasons. The acquisition of the latter, which will be integrated as ...

Sandoz has signed a definitive agreement to acquire Oriel Therapeutics, a privately held US pharmaceuticals company, gaining exclusive rights to a portfolio of generic drug candidates and related technologies targeting medicines in the inhalable respiratory drug market. Terms of the deal were not disclosed. The latter focuses on developing respiratory products with known pathways as generic alternatives to patented drugs for asthma and chronic obstructive pulmonary disease (COPD). The acquisition provides the former with three development projects targeting leading medicines in this field. Regulatory approvals of these medicines, if achieved, would enable the former to increase access to affordable, quality therapeutic alternatives for these increasingly prevalent diseases. Details of the latter's development programs, including anticipated timing of future regulatory submissions, are not disclosed for competitive reasons. The acquisition of the latter, which will be integrated as ...