Bio Saga Blog - A Chronicle of Life Sciences & Informatics

Is organizing "4 Days Workshop on In silico Drug Discovery (21st-24th Jan2016)” Know about drug discovery & optimize your research work CADD is a rapidly developing branch of chemistry. In the coming days the students who have studied CADD will be required not only in India but  across the globe for advanced research and new discovery.The requirement of trained manpower from the discipline such as Chemistry, Biology and Microbiology is the fuel for the growth of CADD.  Application of CADD is in areas like Agrochemical, pharmaceutical and biotechnological industries, Computational chemistry and library design groups, Chemical software companies, Database developers, Chemical publishers, In-silico Drug Discovery, Toxicity predictions, ADME prediction of Molecules, Chemicals Vendors , R&D, etc. On completion of this workshop you will be expertise in: ü        Analyzing chemical fingerprint ü     ...

The Workshop Drug discovery is an expensive and time taking process and therefore new approaches based on chemoinformatics and bioinformatics are being adopted.The knowledge of the 3D structures of protein targets is now playing a major role at all stages of drug discovery. The distinct nature of biological and chemical information requires the integrated capabilities of both bioinformatics and chemo-informatics to decipher existing and hidden relationships. Bioinformatics and chemo-informatics have largely evolved independently from biology and chemistry. Cheminformatics is an inter-disciplinary subject of storage, processing and retrieval of chemical information. Bioinformatics and chemoinformatics have significantly assisted in lead optimization, fingerprinting, pharmacophore designing, target identification, QSAR and their application can lead to discovery of new molecules. Molecular modeling using 3D graphics and optimization techniques helps the scientists to understand how drug...

Here is a abstract that i had submitted at the 3D sig:Structral Bioinformatics at the 1st Structural Bioinformatics Meeting at ISMB 29-30 July 2004, Glasgow, Scotland, UK. I do not know how relevant is the issue to this day. I am interested in working further in this area and i am interested in collaborating. Do let me know your comments also pour your suggestions on how to further this study. In silico methods can be used to design protein, based on stability and functionality using computational methods rather than laboratory procedures (Comet et al., 2000). The changes taking place due to the transfer of motif region from human Catechol-O-methyltansferase to rat Catechol-O-methyltransferase can be studied effectively using computational methods. This will provide insight for further development of the study about the function of neurotransmitter region of catechol-O-methyltransferase and its involvement in the Parkinson’s disease. Catechol-O-methyltransferase (COMT) catalyzes the t...

Yes i am talking about the development in the field of literature search and scientific publication search. Looking beyond NLP some of the advancements and service models based on NLP and other advanced methods. Today to the user's delight there are quite a few companies and organization that provide services that absolutely make an scientist life easy! These services revolve around customized alert services for selected search terms, specific research area of interest even more so pertaining to a list of custom key-word and search terms that the service providers allow the user to choose form. The scientist can simply subscribe to such service, sit back and wait for daily updates. The updates are provided on a day to day basis at his desktop. He gets abstract summarization , full text summarization so that he need not actually go through the ordeal of reading through pages of scientific literature. Some once else does the job for him and just pick up the right things that he woul...

What is this? is this a new industry? or a old wine in a new bottle? may be the later is true, bioinformatics is more popularly known by this name in the industry circle these days! Well Life Sciences and Informatics can be any thing form anything form computational biology, all omes and omics, core bioinformatics to curation and literature mining , database creation, in the area of biology, chemistry , bio-chem space. Cheminformatics , insilico chemistry and insilico biology how best to describe the host of activities involved that companies do to serve their clients and earn revenues for their firms... There are number of companies in India and bangalore is the forefront as a major bio-cluster with 20 to 30 companies operation in this sphere. there are companies with the sole focus as informatics as business to name a few : Molecular Connections Pvt. Ltd. Jubilant Biosys Strand Life Sciences Ocimumbio (hyderbad) While IT companies which are also in to Life Sciences as one of thei...