Bio Saga Blog - A Chronicle of Life Sciences & Informatics

Scientists have discovered a new physical form of proteins that could drastically improve treatments for cancer and other diseases, as well as overcome some of the largest challenges in therapeutics. The protein formulation strategy, developed by researchers at The University of Texas at Austin, is unprecedented and offers a new and universal approach to drug delivery one that could revolutionize treatment of cancer, arthritis and infectious disease. “We believe this discovery of a new highly concentrated form of proteins – clusters of individual protein molecules – is a disruptive innovation that could transform how we fight diseases,” Keith P. Johnston, a chemical engineering professor and member of the National Academy Engineering, said. “It required integration of challenging contributions in fundamental science and engineering from three of our chemical engineering research groups,” he said. Johnston, Chemical Engineering Professor Thomas M. Truskett and Assistant Professor Jennif...

XTractor Knowledgebase XTractor is the first of its kind web 2.0 application which enables researchers to analyze the most current complex biological and chemical relationships published in PUBMED everyday. XTractor Knowledgebase now contains more than 100000 relationships on interactions, regulations and modulations between proteins, drugs, processes and disease. It is the only knowledgebase that updates its data content on a daily basis. The Approach: The Data behind XTractor comes from manual annotation, which is carried out by qualified scientists at Molecular Connections, INDIA ( www.molecularconnections.com ). Our scientists regularly handpick and annotate the most relevant sentences to public ontologies. Each of the data points is quality checked to ensure the highest levels of data accuracy. The extracted facts are also referenced back to the PubMed abstract(s).The sentences in XTractor are also manually c...

Provision to change keywords with user’s changing research preferences in PUBMED data Be a part of the XTractor community. XTractor is the first of its kind - Literature alert service , that provides manually curated and annotated sentences for the Keywords of user preference. XTractor maps the extracted entities (genes, processes, drugs, diseases etc) to multiple ontologies and enables customized report generation. With XTractor the sentences are categorized into biological significant relationships and it also provides the user with the ability to create his own database for a set of Key terms. Also the user could change the Keywords of preference from time to time, with changing research needs. The categorized sentences could then be tagged and shared across multiple users. Thus XTractor proves to be a platform for getting real-time highly accurate data along with the ability to Share and collaborate. Sign up it's free, and takes less than a minute. Just click here: www.xt...