Bio Saga Blog - A Chronicle of Life Sciences & Informatics

3 Days National Level Workshop on "NGS Data Analysis:Variant Calling,RNASEQ,CHIPSEQ"' 8th to 10th March 2019 09:30 AM - 05:00 PM Topics Covered ▪ Introduction to Bioinformatics ▪ Data curation using Biological databases ▪ Understanding the concept of Gene Expression & Genome Editing ▪ Gene Finding Tools ▪ Introduction to Next Generation Sequencing ▪ Searching for SRA Data for genomic samples ▪ Introduction to Sequence alignment, BLAST ▪ Variant Calling to detect mutations ▪ RNA sample studies for gene expression ▪ Introduction to ChIP-Seq technology Our 3 days comprehensive Workshop on Next Generation Sequencing Data Analysis,Variant Calling, RNAseq, ChIPseq : A Practical Introduction aims at providing systematic Hands-on-Training on using Data Analysis application/tools for the NGS data. This workshop had been conceptualized by eminent scientist having substantial experience in the field of Data Analysis. ...

BIBI automates DNA sequence analysis for bacterial identification in the clinical field. BIBI relies on the use of BLAST and CLUSTAL W programs applied to different subsets of sequences extracted from GenBank. These sequences are filtered and stored in a new database, which is adapted to bacterial identification. For further details refer : http://umr5558-sud-str1.univ-lyon1.fr/ lebibi/lebibi.cgi

Cognizant, a leading provider of consulting, technology, and business process outsourcing services, and Eagle Genomics Ltd., a bioinformatics software company specializing in genomic data management and integration, has announced they are working with the Pistoia Alliance, Inc., a nonprofit, precompetitive alliance of life science companies and vendors, as one of the groups engaged to develop a conceptual cloud-based platform to facilitate access to public and proprietary sources of gene sequence data. The Pistoia Alliance’s sequence services working group aims to define and document an externally hosted service for securely storing and mining both proprietary derived gene/sequence information and public domain gene databases. This conceptual platform developed by Cognizant and Eagle Genomics, as part of this piloting stage, will enable working group companies to securely share their bioinformatics resources among simultaneous, registered users in a secure, encrypted environment, while...

Direct-to-consumer genetics testing firm 23andMe has moved to a subscription-based pricing plan that now includes a one year contract and an additional charge of $5 per month. Along with the change in pricing, the company has done away with its separate Ancestry Edition and Health Edition products, which are now part of one service, called Complete Edition, that the firm offers. The base price for the testing service remains at $499 . The Ancestry and Health Edition products were launched a year ago by 23andMe. The changes took effect on Nov. 22. After the initial year expires, the contract will go to a month-to-month model, and customers will be able to cancel their contract at any time, a spokeswoman for Mountain View, Calif.-based 23andMe said. In an e-mail, she said the new monthly charge is based on the company's need to update its test and customers' test results as new genetic discoveries are made. The company's scientific team continually evaluates the latest scien...

Well it so exiting to watch how man makes his future ... The future, always so clear..., had become like a black highway at night. We were in uncharted territory now, making up history as we went along. The future is not set, because we control what happens through the choices we make . The GATTACA era is not far off. 23andMe has dramatically slashed the price for its service and expanded its offerings to include a lineage tracing service through a partnership with Ancestry.com. In a statement today said that by cutting the price for its genotyping service from $999 to $399 it is “democratizing personal genetics and expanding the opportunity for more people to benefit from the genetic revolution.” The company said advances made to Illumina’s genotyping technology , specifically the introduction of the HumanHap550-Quad+ BeadChip , made the price cut possible. Illumina is the provider of genotyping tools for 23andMe’s services. 23andMe also said that beyond the new ancestry ser...

The emergence of “Systems Biology” in recent years highlights the systematic viewpoint of bio-system modeling. Building on such a background, Dual Descriptor Method, a generic methodology for biological sequence analysis is proposed. From a systematic perspective, Dual Descriptor is defined as a two element set of Composition Weight Map and Position Weight Function which aim at reflecting the composition and permutation information of a sequence. An alternate training algorithm is provided to get an optimum description of the building patterns of the sequences. In this paper , dual descriptor method has been applied to the analysis of two typical problems of molecular biology: gene identification and the prediction of protein function. Satisfactory and insightful results are achieved. Owing to the generality of this methodology, dual descriptor method has wide application perspective for many problems of pattern recognition, especially those involved in “Systems Biology”. Be a part of ...