Bio Saga Blog - A Chronicle of Life Sciences & Informatics

CambridgeSoft's Business Partner in Kochi, India is hiring for multiple positions. If you know any appropriate candidates, with a chemistry or biochemistry background. The following is a list of available positions: Team Lead - coordinating the activities of small software development teams: http://www.cambridgesoft.com/careers/details/?Career=115 3D Team Leader : http://www.cambridgesoft.com/careers/details/?Career=228 Developer - Network Communications and Distributed Computing : http://www.cambridgesoft.com/careers/details/?Career=230 Developer Numerical Methods: http://www.cambridgesoft.com/careers/details/?Career=234 Senior Lead Developer : http://www.cambridgesoft.com/careers/details/?Career=225 Scientific Software Developer C++ : http://www.cambridgesoft.com/careers/details/?Career=14 Lead Developer E-Notebook : http://www.cambridgesoft.com/careers/details/?Career=81 E-Notebook Enterprise Support Analyst : http://www.cambridgesoft.com/careers/de...

Here is a abstract that i had submitted at the 3D sig:Structral Bioinformatics at the 1st Structural Bioinformatics Meeting at ISMB 29-30 July 2004, Glasgow, Scotland, UK. I do not know how relevant is the issue to this day. I am interested in working further in this area and i am interested in collaborating. Do let me know your comments also pour your suggestions on how to further this study. In silico methods can be used to design protein, based on stability and functionality using computational methods rather than laboratory procedures (Comet et al., 2000). The changes taking place due to the transfer of motif region from human Catechol-O-methyltansferase to rat Catechol-O-methyltransferase can be studied effectively using computational methods. This will provide insight for further development of the study about the function of neurotransmitter region of catechol-O-methyltransferase and its involvement in the Parkinson’s disease. Catechol-O-methyltransferase (COMT) catalyzes the t...

Brookhaven Lab researchers Subramanyam Swaminathan, Desigan Kumaran and Richa Rawat. "We have found a highly efficient inhibitor of botulinum neurotoxin type A - the most potent of seven neurotoxins produced by the bacterium Clostridium botulinum. This finding can lead to a very effective drug to stop the devastating effects of the toxin," said Dr. Subramanyam Swaminathan, Botulinum neurotoxin -- responsible for the deadly food poisoning disease botulism and for the beneficial effects of smoothing out facial wrinkles - can also be used as a dreaded biological weapon. When ingested or inhaled, less than a billionth of an ounce can cause muscle paralysis and eventual death. Although experimental vaccines administered prior to exposure can inhibit the destructive action of this neurotoxin - the most deadly protein known to humans -- no effective pharmacological treatment exists. Scientists have now taken the first step toward designing an effective antidote to the most potent ...

Indian Drug Database An attempt is made to collect/design the Indian approved drugs and the experimentally determined and computed three-dimensional (3D)-structures and their functional annotations are deposited... Do you want to know more?