Bio Saga Blog - A Chronicle of Life Sciences & Informatics

Applications are invited for the post of Post Doctoral Fellow for the following time-bound sponsored project as per the details given below: Post :  Post Doctoral Fellow Consolidated fellowship :  As per terms governed by the Wellcome trust DBT India Alliance and National Institute of Immunology (a Minimum of Rs. 40,000/- per month).  Project title :  Exploring the role of a developmental regulator in inflammatory immune response under Wellcome Trust DBT India Alliance Essential Qualification :  a. Must hold a Ph.D Degree (not awarded before 2009), or must already have submitted their thesis towards obtaining a Ph.D degree from a reputed Institute. b. Must have more than Five years of research Experience. c.  Must have proven research expertise/skills in basic biochemistry, cell biology and Molecular Biology, Research Expertise in in vivo animal work is also preferred. d. Must have one publication as first author, in international journal, preferab...

2nd International Conference on  Perspective of Cell Signaling and Molecular Medicine   8 to 11 January, 2012  Organised by  Bose Institute, Kolkata Instructions for Submission of Abstract : 1. Only abstracts containing new results will be accepted. Abstracts should clearly and adequately describe the objectives and results of the research. All abstracts must be submitted in English. All abstracts must be accompanied by a completed Conference Registration Form made out in the name of one of the Authors. a. Each abstract should include a title (in capital letters), name(s) of all authors (underline the presenting author), affiliation and email address. b. Type entire abstract single-spaced; typing area: width 12.0 cm (4.7 inches), height 24 cm (9.4 inches). c. Careful typing and proof-reading are essential. Registration : Registration fees : Rs. 4,000/ (Scientist); Rs. 2,500/ (Students including post-docs) Late Registration fees : Rs. 5,000/ and Rs. 3,500/ r...

This something really interesting to PPI, Systems biology  and molecular networks people, I just recently came across, Cellular processes and pathways, whose deregulation may contribute to the development of cancers, are often represented as cascades of proteins transmitting a signal from the cell surface to the nucleus. However, recent functional genomic experiments have identified thousands of interactions for the signalling canonical proteins, challenging the traditional view of pathways as independent functional entities. Combining information from pathway databases and interaction networks obtained from functional genomic experiments is therefore a promising strategy to obtain more robust pathway and process representations, facilitating the study of cancer-related pathways.  Results: We present a methodology for extending pre-defined protein sets representing cellular pathways and processes by mapping them onto a protein-protein interaction network, and extending them t...

Scientists have unravelled the structure of a cell signalling receptor in the blood control system which when damaged is responsible for diseases such as leukaemia. Their discovery helps to explain, for the first time, how this receptor is activated and will form the springboard for the development of new treatments. The findings, published on 8 August in the prestigious science journal, Cell , are the result of an interstate collaboration between a team of scientists led by Professor Michael Parker, St Vincent’s Institute (SVI), Melbourne and Professor Angel Lopez, Hanson Institute at the Institute of Medical and Veterinary Science, Adelaide. Using leading edge technology that allows scientists to view minute parts of cells, the scientists have developed the first 3D image of the receptor’s structure and will use the unique knowledge it provides to find drugs to modify its action and control diseases such as Leukaemia and asthma. Professor Lopez said: “Leukaemia is a...