Bio Saga Blog - A Chronicle of Life Sciences & Informatics

IIIT-Delhi invites applications for admission in Ph.D. - Computational Biology (CB) program. We request you to share the information with potential candidates. Open Positions in below Research Areas: Decoding Cancer Hacking Mechanisms Computational Biochemistry, Mathematical, and systems biology modeling of metabolic networks of cancer systems Computational protein engineering Computational Biology, Network Biology, Systems Biology of Cancer and other Complex Diseases, Computational Gastronomy, Artificial Intelligence, Biomedical Data Informatics, Complex Networks, Natural Language Processing, Machine Learning, Data Analytics, and Mining For more information about our eligibility criteria, admission, selection process, please refer to our website:   https://www.iiitd.ac.in/ admission/phd/nov2019 Center for Computational Biology @IIITD  focuses on educational research at the interface of biological and computational scienc...

SRF Genetics Eligibility : MSc Location : Delhi Last Date :  22 Aug 2016 Hiring Process : Walk - In IARI - Job DetailsDate of posting:01 Aug 16 SRF Genetics recruitment in Indian Agricultural Research Institute SRF Project Title : “CRP - Biofortification in selected crops for nutritional security (rice)” Qualification : Master’s degree in Genetics/Plant Breeding/Genetics and Plant Breeding/Biotechnology/Life Sciences with 4/5 years bachelor’s degree. Those with 3 years bachelor’s degree must have UGC/CSIR/ICAR NET qualification or equivalent or Ph.D. in any of above disciplines (As per ICAR memorandum F.No. Agri. Edn./6/27/2014/HRD Dated 13.07.2015 and F.No. Agri. Edn./6/27/2014/HRD Dated 09.10.2015) Desirable: Experience in use of molecular markers and proficiency in computer skills. No. of Post : 01 Salary : Rs. 25000 SRF Project Title : “Incentivizing Research in Agriculture – Rice” Qualification : Master’s degree in Gen...

Is organizing "4 Days Workshop on In silico Drug Discovery (21st-24th Jan2016)” Know about drug discovery & optimize your research work CADD is a rapidly developing branch of chemistry. In the coming days the students who have studied CADD will be required not only in India but  across the globe for advanced research and new discovery.The requirement of trained manpower from the discipline such as Chemistry, Biology and Microbiology is the fuel for the growth of CADD.  Application of CADD is in areas like Agrochemical, pharmaceutical and biotechnological industries, Computational chemistry and library design groups, Chemical software companies, Database developers, Chemical publishers, In-silico Drug Discovery, Toxicity predictions, ADME prediction of Molecules, Chemicals Vendors , R&D, etc. On completion of this workshop you will be expertise in: ü        Analyzing chemical fingerprint ü     ...

A new paper written by researchers from the Institute for Systems Biology describes a computational approach for studying regulatory activities in cells that relies on integrated networks of transcriptional and metabolic data. The study, published in PLOS Computational Biology earlier this month, describes software called the Gene Expression and Metabolism Integrated for Network Inference (GEMINI) which uses an integrated model of network and metabolic data to explore growth phenotypes in Saccharomyces cerevisiae . GEMINI builds on work from the same researchers published in 2010 in the Proceedings of the National Academy of Sciences . That paper describes the Probabilistic Regulation of Metabolism (PROM), which provides a mechanism for integrating transcriptional regulatory networks and metabolic networks in a single in silico model and using it to make predictions about phenotypes such as flux and growth rate. While based on PROM, GEMINI is designed to tackle a slightly dif...

January 10-12, 2014  Birla Institute of Scientific Research, Statue Circle, Jaipur, India  [link]   Bioinformatics Centre at Birla Institute of Scientific Research, Jaipur is organizing a three-day Bioinformatics workshop on "Structural Bioinformatics". BISR is known for providing a high quality training in advance area of Biotechnology and Bioinformatics.  This workshop will enable participants to learn tools & techniques that are being used to analyze biological structures i.e. proteins and DNA along with application in drug design. The workshop will feature morning lectures, demonstrations with evening hands-on session in Bioinformatics lab.  The no. of participants is limited to 40 only. The participants of the course may be the UG/PG students, research scholars, faculty member and industry personnel with background in Biological Sciences and/or Information Technology. The workshop is self-contained and does not assume any special knowledge of the subjec...

Here are some bioinformatics courses, These are geared towards: - Scientists, so they can think like a programmer and solve bottlenecks in data-based Biology - Computer programmers, so they know how to solve bioinformatics problems for scientists - Bioinformaticians, so they can advance their skills in newer application areas Some of these courses include scripting and database management with Linux, Perl, R, Matlab and MySql, while others include learning to use software for analyzing data from Microarray, NGS, Metabolomics and Proteomics platforms. A course on High Performance Computing and Primer Design is also offered. A detailed roster of scheduled courses is available at: http://www.bioinformatics.org/edu/calendar/view.php?view=upcoming Additionally, through Bioinformatics.org, an instructor-led program in practical bioinformatics is being offered. The goal here is to provide attendees a broad overview of the bioinformatics landscape, while giving them hands-on experienc...

By considering sequence data for individuals assessed through the 1000 Genomes Project, a team led by researchers from Yale University and Wellcome Trust Sanger Institute came up with a computational method for prioritizing potential disease culprits — including those in non-protein-coding parts of the genome. As they reported online today in Science , the researchers sifted through SNP profiles in coding and non-coding sequences in 1,092 genomes, focusing on functionally annotated areas. With the help of information from the ENCODE project, mutation databases, and other data sources, they narrowed in on sequences that seem especially sensitive to change. The group tapped these mutation-sensitive sites to develop an approach called FunSeq, which proved useful for uncovering new apparent driver mutations using sequences from around 90 cancer genomes. These included almost 100 driver candidates in non-coding sequences, according to study authors, who noted that FunSeq is expected...

Courtesy Genomeweb & Julia Karow   Studying for a dual degree in mathematics and molecular biology, Nick Tatonetti became interested in using computational models to study biology and make sense of its massive datasets. As a bioinformatics PhD student at Stanford, he developed new statistical models and computational approaches for analyzing drug effects and drug-drug interactions. At Columbia, Tatonetti is now focusing on molecular mechanisms of drugs. "We can actually think of each time a patient is being given a drug as an experiment," he says. "When the drug goes into the human system, it interacts molecularly, and then phenotypes come out of this system," which can be connected to molecular mechanisms in new ways. In particular, he is developing techniques that use clinical data to develop networks that highlight interactions between different systems in the human body, such as two organs. "And once we know that certain gene produc...

Microbial Genomes Curator @ Computercraft Corporation--Maryland (US).  Submitted by Computercraft Corporation; posted on Saturday, March 17, 2012 RESPONSIBILITIES: Computercraft seeks a microbiologist to work with a team of software developers and biologists on microbial genome analysis including pan-genome, protein clusters, phylogenetic tree and more. This is a technically challenging position requiring experience in genome sequencing and annotation. A background in comparative genome analysis such as alignments and tree building is a plus. Our scientists work with genomic experts at the NIH's National Center for Biotechnology Information (NCBI) to create and enhance a suite of databases and tools available to researchers worldwide. Teamwork interaction and excellent organizational skills are essential for this detail-oriented position, as is scientific problem-solving with a results-oriented focus. REQUIREMENTS: * PhD in molecular biology, microbiology, or related field * ...

In structural biology, similarity analysis of protein structure is a crucial step in studying the relationship between proteins. Despite the considerable number of techniques that have been explored within the past two decades, the development of new alternative methods is still an active research area due to the need for high performance tools. Results: In this paper, we present TS-AMIR, a Topology String Alignment Method for Intensive Rapid comparison of protein structures. The proposed method works in two stages: In the first stage, the method generates a topology string based on the geometric details of secondary structure elements, and then, utilizes an n-gram modelling technique over entropy concept to capture similarities in these strings. This initial correspondence map between secondary structure elements is submitted to the second stage in order to obtain the alignment at the residue level. Applying the Kabsch method, a heuristic step-by-step algorithm is adopted in the secon...

The Pune-based Centre for Development of Advanced Computing (C-DAC), maker of series of high-end PARAM supercomputer, has developed a new powerful supercomputer called Biochrome to aid computational biology research with an investment of Rs 1 crore, a top official said. “The Biochrome machine is an advanced blade server based high performance computing (HPC) facility developed by our scientists to aid biology researchers in the country and abroad,” Professor Rajat Moona, director general of C-DAC, said. The machine has a peak computing capacity of 5 TeraFlop or the capacity to perform 5 trillion operations per second. “About 10 scientists from C-DAC spent over six months to design and produce Biochrome machine with a total investment of Rs 1 crore funded by the Department of Information Technology, government of India,” Rajendra Joshi, associate director and head of the department of Bioinformatics, C-DAC, who headed the research team, said. He said Biochrome is the latest product ...

Centre for Bioinformatics focuses on to develop core competencies employing high performance computational systems with the ultimate goal of elucidating differences between health and disease. Candidates with passion towards Scientific Research and attitude to work in a multidisciplinary team are invited to submit their Curriculum Vitae along with 2 references. The selected candidate will also have higher chance of being recruited as research fellows in future grants, which shall also lead to Ph.D, registration. This will be solely based on the performance review of the candidates after one year of service completion. Name of the Post :  Junior Scientist Salary :  Rs.10, 000/- Qualification  : M.Sc/B.Tech in Bioinformatics / LifeSciences Post Graduates with Skills mentioned below will also be considered Skills required :  Hands on Experience in Molecular Modelling, Docking, Molecular Dynamics Simulation and Cheminformatics Tools (OpenSource) in Linux Platform. Kno...

December 12, 2011 Applications are invited for the GN Ramachandran Fellowships recently instituted by the CCBB, DBT-COE, JNU to encourage young scholars to work in the interdisciplinary research in the field of computational biology. The fellowship is meant for brilliant scientists and engineers from all over the world to take up scientific research positions at SCIS, JNU. SCOPE :  Computational Biology & Data Mining. QUALIFICATION & BACKGROUND: i) The fellowship is open to brilliant scientists and engineers who are below the age of 35 years . ii) The applicant should possess a Ph.D. in Science/Engineering and have adequate professional experience. iii) These Fellowships are very selective and only those who have a proven/outstanding track-record as evident from their research publications and recognitions would be eligible. ELIGIBILITY FOR JUNIOR FELLOW : 1. Ph.D. in any branch of natural sciences. 2. At least 2 years Post-Doc experience in theoretical/computation...