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IIIT-Delhi invites applications for admission in Ph.D. - Computational Biology (CB) program. We request you to share the information with potential candidates. Open Positions in below Research Areas: Decoding Cancer Hacking Mechanisms Computational Biochemistry, Mathematical, and systems biology modeling of metabolic networks of cancer systems Computational protein engineering Computational Biology, Network Biology, Systems Biology of Cancer and other Complex Diseases, Computational Gastronomy, Artificial Intelligence, Biomedical Data Informatics, Complex Networks, Natural Language Processing, Machine Learning, Data Analytics, and Mining For more information about our eligibility criteria, admission, selection process, please refer to our website:   https://www.iiitd.ac.in/ admission/phd/nov2019 Center for Computational Biology @IIITD  focuses on educational research at the interface of biological and computational scienc...

Recently I had shared a piece of news on the same topic:-  https://www.linkedin.com/feed/update/urn:li:activity:6590633791084163072/ # lims hashtag # laboratories hashtag # datamanagement hashtag # flexible Data Management Challenges In Next Generation Sequencing Since the beginning of the Human Genome Project, data management has been perceived as a key challenge for current molecular biology research. Before the finish of the nineties, advances had been set up that adequately bolstered most continuous activities, ordinarily based upon relational database management frameworks. Ongoing years have seen a sensational increment in the amount of information created by running projects that extends in this area. While it took over ten years, roughly three billion USD, and in excess of 200 gatherings worldwide to collect the main human genome, the present sequencing machines create a similar amount of crude information in seven days, at an expense of around 2000 USD...

"Prime editing" is more precise and more efficient than CRISPR and could herald a new era of genetic manipulation. The ability to edit the genes of human beings by changing the code of life -- DNA -- has dramatically improved over the last decade. Current tools, like  CRISPR-Cas9 and  base editors , are extremely powerful but have traditionally suffered from a lack of precision, high error rate and limited scope, hampering their ability to treat human genetic disease. A breakthrough gene-editing tool, developed by a team of researchers at Harvard University and unveiled Monday, has the ability to make extremely precise DNA edits, ushering in a new era of genetic manipulation. "In many respects this first report is the beginning rather than the end of a longstanding aspiration ... to be able to make any DNA change in any position of a living cell or organism including, potentially, human patients with genetic diseases," says David Liu, a chemist at Harvard'...

https://youtu.be/TdBAHexVYzc

https://time.com/5642755/crispr-gene-editing-humans/?amp=true It’s only been seven years since scientists first learned how to precisely and reliably splice the human genome using a tool called CRISPR , making it possible to think about snipping out disease-causing mutations and actually cure, once and for all, genetic diseases ranging from sickle cell anemia to certain types of cancer and even blindness. Doctors are plunging ahead in search of ways to use the relatively new technology to start treating patients. In China last November, scientist Jiankui He stunned—and dismayed—the genetic community when he announced he had already used CRISPR, which many believe still hasn’t been proven either safe or effective in human patients, to permanently alter the genomes of twin girls to be immune to HIV infection. He’s experiment was criticized because he edited the twins’ cells when they were embryos, therefore ensuring that every one of their cells is now changed, including their ...

https://singularityhub.com/2019/05/02/crispr-used-in-human-trials-for-the-first-time-in-the-us/amp/ CRISPR  just hit another landmark. Last week, the University of Pennsylvania (UPenn) confirmed that they have treated two cancer patients using the gene editing darling married with another biomedical wizard,  CAR-T . For now, it’s too early to tell if the treatment proved beneficial in either patient, but the team hopes to release a first batch of results in a conference or journal “ at an appropriate time .” It marks CRISPR’s first debut onto the US clinical scene, and it’s a long time coming. As early as mid-2016 the team had already received approval from the FDA to move ahead with their concept. Yet they didn’t register the trial  until early 2018 , taking careful precautions to not royally mess up CRISPR’s introduction into the biomedical mainstream. This is in stark contrast to China, which, due to laxer clinical registration rules,  kicked off its ...

Japan has given the green light to a controversial research process involving implanting animals with human stem cells that could eventually help grow human organs for transplant inside animal hosts.

              Know About Our Workshop On Bioinformatics and Protein Structure Prediction 10th to 12th May 2019 | Pune, India | 09:30 AM - 05:00 PM Our 3 day comprehensive workshop on Bioinformatics and Protein Structure Prediction aims at providing systematic Hands-on-Training on Protein visualization, mutation & other manipulations.Understand concept of in-silico protein modelling using servers & software’s.Understanding concept of protein motif and domains.Understanding concept of protein structure prediction by Modeller COMPREHENSIVE & SEQUENTIAL SESSIONS ON: ▪ Introduction to Biological databases ▪ Multiple Sequence Alignment – CLUSTALW ▪ Introduction to Proteins & Protein Databases-UNIPROT ▪ Study of proteins and their structures ▪ Protein Secondary Structure Prediction tools ▪ Protein Tertiary Structure Prediction using Servers & Modeller ▪ Protein Structure Validation ...